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Three Phases of CD8 T Cell Response in the Lung Following H1N1 Influenza Infection and Sphingosine 1 Phosphate Agonist Therapy
Influenza-induced lung edema and inflammation are exacerbated by a positive feedback loop of cytokine and chemokine production termed a ‘cytokine storm’, a hallmark of increased influenza-related morbidity and mortality. Upon infection, an immune response is rapidly initiated in the lungs and draini...
Autores principales: | Matheu, Melanie P., Teijaro, John R., Walsh, Kevin B., Greenberg, Milton L., Marsolais, David, Parker, Ian, Rosen, Hugh, Oldstone, Michael B A., Cahalan, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606384/ https://www.ncbi.nlm.nih.gov/pubmed/23533579 http://dx.doi.org/10.1371/journal.pone.0058033 |
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