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Curcumin as a Potent and Selective Inhibitor of 11β-Hydroxysteroid Dehydrogenase 1: Improving Lipid Profiles in High-Fat-Diet-Treated Rats

BACKGROUND: 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) activates glucocorticoid locally in liver and fat tissues to aggravate metabolic syndrome. 11β-HSD1 selective inhibitor can be used to treat metabolic syndrome. Curcumin and its derivatives as selective inhibitors of 11β-HSD1 have not been re...

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Detalles Bibliográficos
Autores principales:	Hu, Guo-Xin, Lin, Han, Lian, Qing-Quan, Zhou, Shu-Hua, Guo, Jingjing, Zhou, Hong-Yu, Chu, Yanhui, Ge, Ren-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606385/ https://www.ncbi.nlm.nih.gov/pubmed/23533564 http://dx.doi.org/10.1371/journal.pone.0049976

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