Cargando…

Role of the Phosphatase PTEN in Early Vascular Remodeling

BACKGROUND: The phosphatase PTEN represents an important physiological inhibitor of phosphatidylinositol-3 kinase (PI3-K)/protein kinase B (Akt) signalling, however, the functional role of PTEN in the initial phase of angioplasty-induced vascular injury remains elusive. In the present study we sough...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sedding, Daniel G., Widmer-Teske, Rebecca, Mueller, Andreas, Stieger, Philipp, Daniel, Jan-Marcus, Gündüz, Dursun, Pullamsetti, Soni, Nef, Holger, Moellmann, Helge, Troidl, Christian, Hamm, Christian, Braun-Dullaeus, Rüdiger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606387/ https://www.ncbi.nlm.nih.gov/pubmed/23533567 http://dx.doi.org/10.1371/journal.pone.0055445

Ejemplares similares

Inhibition of STAT3 signaling prevents vascular smooth muscle cell proliferation and neointima formation
por: Daniel, Jan-Marcus, et al.
Publicado: (2012)

Uridine Triphosphate Thio Analogues Inhibit Platelet P2Y(12) Receptor and Aggregation
por: Gündüz, Dursun, et al.
Publicado: (2017)

cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation
por: Aslam, Muhammad, et al.
Publicado: (2014)

Role of PI3K/Akt and MEK/ERK Signalling in cAMP/Epac-Mediated Endothelial Barrier Stabilisation
por: Gündüz, Dursun, et al.
Publicado: (2019)

Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function
por: Aslam, Muhammad, et al.
Publicado: (2019)

Purinergic Regulation of Endothelial Barrier Function
por: Aslam, Muhammad, et al.
Publicado: (2021)

Targeting of Extracellular RNA Reduces Edema Formation and Infarct Size and Improves Survival After Myocardial Infarction in Mice
por: Stieger, Philipp, et al.
Publicado: (2017)

Classically and alternatively activated macrophages contribute to tissue remodelling after myocardial infarction
por: Troidl, C, et al.
Publicado: (2009)

Sham Surgery and Inter-Individual Heterogeneity Are Major Determinants of Monocyte Subset Kinetics in a Mouse Model of Myocardial Infarction
por: Hoffmann, Jedrzej, et al.
Publicado: (2014)

Functional analysis of the protein phosphatase activity of PTEN
por: Zhang, Xiaoqun Catherine, et al.
Publicado: (2012)

Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
por: Paddenberg, Renate, et al.
Publicado: (2007)

Innovative fakultative Seminarkonzepte besonders klinisch-praktisch ausgerichteter Lehre zur Famulatur- und PJ-Vorbereitung aus spezifisch chirurgischer Sicht
por: Stieger, Philipp, et al.
Publicado: (2022)

Erratum zu: Innovative fakultative Seminarkonzepte besonders klinisch-praktisch ausgerichteter Lehre zur Famulatur- und PJ-Vorbereitung aus spezifisch chirurgischer Sicht
por: Stieger, Philipp, et al.
Publicado: (2023)

Interactions of Phosphatase and Tensin Homologue (PTEN) Proteins with Phosphatidylinositol Phosphates: Insights from Molecular Dynamics Simulations of PTEN and Voltage Sensitive Phosphatase
por: Kalli, Antreas C., et al.
Publicado: (2014)

Neutrophil Gelatinase-Associated Lipocalin Cutoff Value Selection and Acute Kidney Injury Classification System Determine Phenotype Allocation and Associated Outcomes
por: Albert, Annemarie, et al.
Publicado: (2023)

Effect of Anti-Hypertensive Medication on Plasma Concentrations of Lysyl Oxidase: Evidence for Aldosterone-IL-6-Dependent Regulation of Lysyl Oxidase Blood Concentration
por: Schreckenberg, Rolf, et al.
Publicado: (2022)

Students’ perception and learning experience in the first medical clerkship
por: Gottschalk, Marc, et al.
Publicado: (2022)

IL10 Alters Peri-Collateral Macrophage Polarization and Hind-Limb Reperfusion in Mice after Femoral Artery Ligation
por: Götze, Alexander M., et al.
Publicado: (2020)

Glycogen Synthase Kinase 3beta Contributes to Proliferation of Arterial Smooth Muscle Cells in Pulmonary Hypertension
por: Sklepkiewicz, Piotr, et al.
Publicado: (2011)

Biomarker-Guided Risk Assessment for Acute Kidney Injury: Time for Clinical Implementation?
por: Albert, Christian, et al.
Publicado: (2021)

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases
por: Miletic, Ana V., et al.
Publicado: (2010)

Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance
por: Henle, Steven J., et al.
Publicado: (2013)

PTEN Dual Lipid- and Protein-Phosphatase Function in Tumor Progression
por: Liu, Anne, et al.
Publicado: (2022)

Medical education during the Covid-19 pandemic long-term experiences of German clinical medical students
por: Gottschalk, Marc, et al.
Publicado: (2023)

Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration
por: Pullamsetti, Soni, et al.
Publicado: (2005)

A method to control phosphoinositides and to analyze PTEN function in living cells using voltage sensitive phosphatases
por: Mavrantoni, Angeliki, et al.
Publicado: (2015)

Digitalization of presence events in the COVID-19 pandemia – the lecturers’ perspective
por: Gottschalk, Marc, et al.
Publicado: (2021)

What understanding of economics do medical students have?
por: Spura, Anke, et al.
Publicado: (2019)

Confusion in connection with pulmonary hypertension due to premature ventricular complexes requires diagnostic work-up
por: Luani, Blerim, et al.
Publicado: (2023)

Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity
por: Wong, J. T., et al.
Publicado: (2006)

PTEN inhibits BMI1 function independently of its phosphatase activity
por: Fan, Catherine, et al.
Publicado: (2009)

Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis
por: Stumpf, Miriam, et al.
Publicado: (2016)

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes
por: Lee, Chang-Uk, et al.
Publicado: (2015)

PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
por: Wise, Helen M., et al.
Publicado: (2022)

The Role of Oxidative Inactivation of Phosphatase PTEN and TCPTP in Fatty Liver Disease
por: Nguyen Huu, Thang, et al.
Publicado: (2023)

New Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway
por: Alfieri, Roberta, et al.
Publicado: (2017)

Urinary and plasma hepcidin-25 as indicators of labile iron involvement in acute kidney injury after cardiac surgery
por: Albert, Annemarie, et al.
Publicado: (2023)

The G534E polymorphism of the gene encoding the factor VII–activating protease is associated with cardiovascular risk due to increased neointima formation
por: Sedding, Daniel, et al.
Publicado: (2006)

Was der (Allgemein- und Viszeral‑)Chirurg über die Thromboseprophylaxe wissen sollte
por: Meißler, Saskia, et al.
Publicado: (2022)

Phosphodiesterase 10A Upregulation Contributes to Pulmonary Vascular Remodeling
por: Tian, Xia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_pjec8fe8g2inerea1kqf4fs638