Dual Role of G-runs and hnRNP F in the Regulation of a Mutation-Activated Pseudoexon in the Fibrinogen Gamma-Chain Transcript

Most pathological pseudoexon inclusion events originate from single activating mutations, suggesting that many intronic sequences are on the verge of becoming exons. However, the precise mechanisms controlling pseudoexon definition are still largely unexplored. Here, we investigated the cis-acting e...

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Detalles Bibliográficos
Autores principales: Rimoldi, Valeria, Soldà, Giulia, Asselta, Rosanna, Spena, Silvia, Stuani, Cristiana, Buratti, Emanuele, Duga, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606458/
https://www.ncbi.nlm.nih.gov/pubmed/23533617
http://dx.doi.org/10.1371/journal.pone.0059333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606458/
https://www.ncbi.nlm.nih.gov/pubmed/23533617
http://dx.doi.org/10.1371/journal.pone.0059333

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