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The pseudopeptide HB-19 binds to cell surface nucleolin and inhibits angiogenesis

BACKGROUND: Nucleolin is a protein over-expressed on the surface of tumor and endothelial cells. Recent studies have underlined the involvement of cell surface nucleolin in tumor growth and angiogenesis. This cell surface molecule serves as a receptor for various ligands implicated in pathophysiolog...

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Detalles Bibliográficos
Autores principales: Birmpas, Charalampos, Briand, Jean Paul, Courty, Josẻ, Katsoris, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606460/
https://www.ncbi.nlm.nih.gov/pubmed/23265284
http://dx.doi.org/10.1186/2045-824X-4-21