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The pseudopeptide HB-19 binds to cell surface nucleolin and inhibits angiogenesis
BACKGROUND: Nucleolin is a protein over-expressed on the surface of tumor and endothelial cells. Recent studies have underlined the involvement of cell surface nucleolin in tumor growth and angiogenesis. This cell surface molecule serves as a receptor for various ligands implicated in pathophysiolog...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606460/ https://www.ncbi.nlm.nih.gov/pubmed/23265284 http://dx.doi.org/10.1186/2045-824X-4-21 |