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Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles
BACKGROUND: In the mouse ovary, oocytes initially develop in clusters termed germ-cell nests. Shortly after birth, these germ-cell nests break apart, and the oocytes individually become surrounded by somatic granulosa cells to form primordial follicles. Notch signaling plays essential roles during o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606475/ https://www.ncbi.nlm.nih.gov/pubmed/23406467 http://dx.doi.org/10.1186/1741-7007-11-13 |