Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report

Interferon alpha (IFNα) has immune stimulatory actions implicated in its pulmonary toxicities. We describe deterioration of idiopathic pulmonary fibrosis (IPF) associated with IFNα treatment for chronic hepatitis C in a 58 year old woman culminating in a fatal suspected acute exacerbation of IPF (AE...

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Autores principales: Ling, Victoria Yee-May, Mortimore, Marianne, Serisier, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606512/
https://www.ncbi.nlm.nih.gov/pubmed/23538739
http://dx.doi.org/10.1186/2193-1801-2-101
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author Ling, Victoria Yee-May
Mortimore, Marianne
Serisier, David J
author_facet Ling, Victoria Yee-May
Mortimore, Marianne
Serisier, David J
author_sort Ling, Victoria Yee-May
collection PubMed
description Interferon alpha (IFNα) has immune stimulatory actions implicated in its pulmonary toxicities. We describe deterioration of idiopathic pulmonary fibrosis (IPF) associated with IFNα treatment for chronic hepatitis C in a 58 year old woman culminating in a fatal suspected acute exacerbation of IPF (AE-IPF). Caution should be exercised in the use of IFNα in subjects with concomitant IPF given its known immunostimulatory effects and possible role in this suspected AE-IPF.
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spelling pubmed-36065122013-03-25 Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report Ling, Victoria Yee-May Mortimore, Marianne Serisier, David J Springerplus Case Study Interferon alpha (IFNα) has immune stimulatory actions implicated in its pulmonary toxicities. We describe deterioration of idiopathic pulmonary fibrosis (IPF) associated with IFNα treatment for chronic hepatitis C in a 58 year old woman culminating in a fatal suspected acute exacerbation of IPF (AE-IPF). Caution should be exercised in the use of IFNα in subjects with concomitant IPF given its known immunostimulatory effects and possible role in this suspected AE-IPF. Springer International Publishing AG 2013-03-12 /pmc/articles/PMC3606512/ /pubmed/23538739 http://dx.doi.org/10.1186/2193-1801-2-101 Text en © Ling et al.; licensee Springer. 2013 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Study
Ling, Victoria Yee-May
Mortimore, Marianne
Serisier, David J
Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report
title Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report
title_full Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report
title_fullStr Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report
title_full_unstemmed Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report
title_short Suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis C: case report
title_sort suspected acute exacerbation of idiopathic pulmonary fibrosis associated with interferon alpha therapy for hepatitis c: case report
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606512/
https://www.ncbi.nlm.nih.gov/pubmed/23538739
http://dx.doi.org/10.1186/2193-1801-2-101
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AT serisierdavidj suspectedacuteexacerbationofidiopathicpulmonaryfibrosisassociatedwithinterferonalphatherapyforhepatitisccasereport

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