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Structure of Pseudomonas aeruginosa inosine 5′-monophosphate dehydrogenase

Inosine 5′-monophosphate dehydrogenase (IMPDH) represents a potential antimicrobial drug target. The crystal structure of recombinant Pseudomonas aeruginosa IMPDH has been determined to a resolution of 2.25 Å. The structure is a homotetramer of subunits dominated by a (β/α)(8)-barrel fold, consisten...

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Detalles Bibliográficos
Autores principales:	Rao, Vincenzo A., Shepherd, Sharon M., Owen, Richard, Hunter, William N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2013
Materias:	Structural Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606566/ https://www.ncbi.nlm.nih.gov/pubmed/23519796 http://dx.doi.org/10.1107/S1744309113002352

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