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Multi-Domain Integration in the Structure of the HNF4α Nuclear Receptor Complex
The hepatocyte nuclear factor 4 alpha (HNF4α, NR2A1) is a member of the nuclear receptor (NR) family of transcription factors that use conserved DNA binding domains (DBDs) and ligand binding domains (LBDs)(1,2). HNF4α is the most abundant DNA-binding protein in the liver, where some 40% of the activ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606643/ https://www.ncbi.nlm.nih.gov/pubmed/23485969 http://dx.doi.org/10.1038/nature11966 |