Infiltration of Proinflammatory M1 Macrophages into the Outer Retina Precedes Damage in a Mouse Model of Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of blindness in the developed world. Oxidative stress and inflammation are implicated in AMD, but precise mechanisms remain poorly defined. Carboxyethylpyrrole (CEP) is an AMD-associated lipid peroxidation product. We previously demonstrated th...

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Detalles Bibliográficos
Autores principales: Cruz-Guilloty, Fernando, Saeed, Ali M., Echegaray, Jose J., Duffort, Stephanie, Ballmick, Asha, Tan, Yaohong, Betancourt, Michel, Viteri, Eduardo, Ramkhellawan, Ghansham C., Ewald, Eric, Feuer, William, Huang, DeQiang, Wen, Rong, Hong, Li, Wang, Hua, Laird, James M., Sene, Abdoulaye, Apte, Rajendra S., Salomon, Robert G., Hollyfield, Joe G., Perez, Victor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606733/
https://www.ncbi.nlm.nih.gov/pubmed/23533946
http://dx.doi.org/10.1155/2013/503725

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