Periodontal Regeneration Using Platelet-Derived Growth Factor in Infrabony Defects: A Series of Three Cases

The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue...

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Detalles Bibliográficos
Autores principales: Thakare, Kaustubh, Bhongade, M. L., Charde, Preeti, Jaiswal, Priyanka, Shah, Nachiket, Deshpande, Aniruddha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606737/
https://www.ncbi.nlm.nih.gov/pubmed/23533830
http://dx.doi.org/10.1155/2013/849823
Descripción
Sumario:The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue repair. Platelet-derived growth factor (PDGF) is the most thoroughly studied growth factor in periodontal regeneration. The present case series evaluate the effectiveness of platelet-derived growth factor (rh-PDGF-BB) in combination with beta-tricalcium phosphate (β-TCP) to achieve periodontal regeneration in 3 infrabony defects.

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