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High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus

Ebolavirus, a member of the Filoviridae family of negative-sense RNA viruses, causes severe haemorrhagic fever leading up to 90% lethality. Ebolavirus matrix protein VP40 is involved in the virus assembly and budding process. The RNA binding pocket of VP40 is considered as the drug target site for s...

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Detalles Bibliográficos
Autores principales: Tamilvanan, Thangaraju, Hopper, Waheeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607187/
https://www.ncbi.nlm.nih.gov/pubmed/23559747
http://dx.doi.org/10.6026/97320630009286