Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

The molecular chaperone Hsp90 is a hub of protein homeostasis and regulatory circuitry. Hsp90 function is regulated by posttranslational modifications including acetylation in mammals; however, whether this regulation is conserved remains unknown. In fungi, Hsp90 governs the evolution of drug resist...

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Detalles Bibliográficos
Autores principales: Robbins, Nicole, Leach, Michelle D., Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607219/
https://www.ncbi.nlm.nih.gov/pubmed/23041319
http://dx.doi.org/10.1016/j.celrep.2012.08.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607219/
https://www.ncbi.nlm.nih.gov/pubmed/23041319
http://dx.doi.org/10.1016/j.celrep.2012.08.035

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