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Distinct roles for complement in glomerulonephritis and atherosclerosis revealed in mice with a combination of lupus and hyperlipidemia

Objective Although the accelerating effect of systemic lupus erythematosus (SLE) on atherosclerosis is well established, the underlying mechanisms are unknown. The aim of this study was to explore the hypothesis that lupus autoimmunity modulates the effect of hypercholesterolemia in driving arterial...

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Detalles Bibliográficos
Autores principales: Lewis, Myles J, Malik, Talat H, Fossati-Jimack, Liliane, Carassiti, Daniele, Cook, H Terence, Haskard, Dorian O, Botto, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607248/
https://www.ncbi.nlm.nih.gov/pubmed/22392450
http://dx.doi.org/10.1002/art.34451