Cargando…

Ionizing Radiation Potentiates Dihydroartemisinin-Induced Apoptosis of A549 Cells via a Caspase-8-Dependent Pathway

This report is designed to explore the molecular mechanism by which dihydroartemisinin (DHA) and ionizing radiation (IR) induce apoptosis in human lung adenocarcinoma A549 cells. DHA treatment induced a concentration- and time-dependent reactive oxygen species (ROS)-mediated cell death with typical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Tongsheng, Chen, Min, Chen, Jingqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607559/ https://www.ncbi.nlm.nih.gov/pubmed/23536891 http://dx.doi.org/10.1371/journal.pone.0059827

Ejemplares similares

Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells
por: Lu, Ying-Ying, et al.
Publicado: (2009)

Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway
por: Dou, C, et al.
Publicado: (2016)

p62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis
por: Lee, Su Hyun, et al.
Publicado: (2021)

Cordyceps militaris extract induces apoptosis and pyroptosis via caspase‐3/PARP/GSDME pathways in A549 cell line
por: Hu, Zixuan, et al.
Publicado: (2021)

Dihydroartemisinin inhibits multiplication of Brucella suis vaccine strain 2 in murine microglia BV2 cells via stimulation of caspase-dependent apoptosis
por: Yang, Juan, et al.
Publicado: (2019)

Scutellarin-induced A549 cell apoptosis depends on activation of the transforming growth factor-β1/smad2/ROS/caspase-3 pathway
por: Zhang, Guang-Yan, et al.
Publicado: (2021)

The paradox role of caspase cascade in ionizing radiation therapy
por: Rahmanian, Najmeh, et al.
Publicado: (2016)

Facile and green reduction of covalently PEGylated nanographene oxide via a ‘water-only’ route for high-efficiency photothermal therapy
por: Chen, Jingqin, et al.
Publicado: (2014)

Dihydroartemisinin Reduces Irradiation-Induced Mitophagy and Radioresistance in Lung Cancer A549 Cells via CIRBP Inhibition
por: Wu, Shunlong, et al.
Publicado: (2022)

Ionizing radiation induces stem cell-like properties in a caspase-dependent manner in Drosophila
por: Verghese, Shilpi, et al.
Publicado: (2018)

miR-101 sensitizes A549 NSCLC cell line to CDDP by activating caspase 3-dependent apoptosis
por: YIN, JIQING, et al.
Publicado: (2014)

Caspase-Dependent Apoptosis Induced by Simarouba Glauca on Human Non-Small-Cell Lung Cancer, A549 Cells
por: Vikas, Biba, et al.
Publicado: (2022)

Gleditsia Saponin C Induces A549 Cell Apoptosis via Caspase-Dependent Cascade and Suppresses Tumor Growth on Xenografts Tumor Animal Model
por: Cheng, Ye, et al.
Publicado: (2018)

Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism
por: Dubey, Megha, et al.
Publicado: (2016)

Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway
por: Meng, Ling, et al.
Publicado: (2010)

Nickel chloride-induced apoptosis via mitochondria- and Fas-mediated caspase-dependent pathways in broiler chickens
por: Guo, Hongrui, et al.
Publicado: (2016)

Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and –independent apoptosis via Smad or Akt signaling pathways in HOS cells
por: Huang, Cheng, et al.
Publicado: (2020)

Apoptosis Induction by dsRNA-Dependent Protein Kinase R (PKR) in EPC Cells via Caspase 8 and 9 Pathways
por: Xu, Cheng, et al.
Publicado: (2018)

Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway
por: Tang, Shiqi, et al.
Publicado: (2019)

Tricholoma matsutake Aqueous Extract Induces Hepatocellular Carcinoma Cell Apoptosis via Caspase-Dependent Mitochondrial Pathway
por: Wang, Yanzhen, et al.
Publicado: (2016)

Dihydroartemisinin: A Potential Natural Anticancer Drug
por: Dai, Xiaoshuo, et al.
Publicado: (2021)

Growth arrest and apoptosis via caspase activation of dioscoreanone in human non-small-cell lung cancer A549 cells
por: Hansakul, Pintusorn, et al.
Publicado: (2014)

Mitochondrial transcription factor A regulated ionizing radiation-induced mitochondrial biogenesis in human lung adenocarcinoma A549 cells
por: Yu, Jing, et al.
Publicado: (2013)

Rhein induces liver cancer cells apoptosis via activating ROS-dependent JNK/Jun/caspase-3 signaling pathway
por: Wang, Aili, et al.
Publicado: (2020)

Novel dihydroartemisinin derivative DHA-37 induces autophagic cell death through upregulation of HMGB1 in A549 cells
por: Liu, Xiufeng, et al.
Publicado: (2018)

Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages
por: Chen, Jing, et al.
Publicado: (2021)

Polyphenolic compounds from Korean Lonicera japonica Thunb. induces apoptosis via AKT and caspase cascade activation in A549 cells
por: Park, Kwang Il, et al.
Publicado: (2017)

Rhein suppresses African swine fever virus replication in vitro via activating the caspase-dependent mitochondrial apoptosis pathway
por: Song, Zebu, et al.
Publicado: (2023)

Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells
por: Cho, Sung-Hee, et al.
Publicado: (2009)

A New Caspase-8 Isoform Caspase-8s Increased Sensitivity to Apoptosis in Jurkat Cells
por: Xu, Zhifang, et al.
Publicado: (2009)

Sam68 is cleaved by caspases under apoptotic cell death induced by ionizing radiation
por: Cho, Seong-Jun, et al.
Publicado: (2015)

Dihydroartemisinin induces apoptosis and inhibits proliferation, migration, and invasion in epithelial ovarian cancer via inhibition of the hedgehog signaling pathway
por: Liu, Yanmei, et al.
Publicado: (2018)

Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy
por: Chen, Tao, et al.
Publicado: (2009)

Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway
por: Yu, Ziyan, et al.
Publicado: (2018)

The role of caspase-dependent and caspase-independent pathways of apoptosis in the premature rupture of the membranes: A case-control study
por: Negara, Ketut Surya, et al.
Publicado: (2020)

Dihydroartemisinin inhibits EMT induced by platinum-based drugs via Akt–Snail pathway
por: Qin, Yuan, et al.
Publicado: (2017)

A Structural Model for Bax∆2-Mediated Activation of Caspase 8-Dependent Apoptosis
por: Xie, Bing, et al.
Publicado: (2020)

Melatonin protects against apoptosis of megakaryocytic cells via its receptors and the AKT/mitochondrial/caspase pathway
por: Yang, Mo, et al.
Publicado: (2020)

Strophalloside Induces Apoptosis of SGC-7901 Cells through the Mitochondrion-Dependent Caspase-3 Pathway
por: Zhang, Xue-Jiao, et al.
Publicado: (2015)

Silencing of Pokemon Enhances Caspase-Dependent Apoptosis via Fas- and Mitochondria-Mediated Pathways in Hepatocellular Carcinoma Cells
por: Zhang, Yu-Qin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9mvc3qq5jcnht1bndqgfiqf8v0