Ras-Association Domain of Sorting Nexin 27 Is Critical for Regulating Expression of GIRK Potassium Channels

G protein-gated inwardly rectifying potassium (GIRK) channels play an important role in regulating neuronal excitability. Sorting nexin 27b (SNX27b), which reduces surface expression of GIRK channels through a PDZ domain interaction, contains a putative Ras-association (RA) domain with unknown funct...

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Detalles Bibliográficos
Autores principales: Balana, Bartosz, Bahima, Laia, Bodhinathan, Karthik, Taura, Jaume J., Taylor, Natalie M., Nettleton, Margaret Y., Ciruela, Francisco, Slesinger, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607560/
https://www.ncbi.nlm.nih.gov/pubmed/23536889
http://dx.doi.org/10.1371/journal.pone.0059800

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