Functional Impacts of NRXN1 Knockdown on Neurodevelopment in Stem Cell Models

Exonic deletions in NRXN1 have been associated with several neurodevelopmental disorders, including autism, schizophrenia and developmental delay. However, the molecular mechanism by which NRXN1 deletions impact neurodevelopment remains unclear. Here we used human induced pluripotent stem cells (hiP...

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Detalles Bibliográficos
Autores principales: Zeng, Liyun, Zhang, Peilin, Shi, Lingling, Yamamoto, Vicky, Lu, Wange, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607566/
https://www.ncbi.nlm.nih.gov/pubmed/23536886
http://dx.doi.org/10.1371/journal.pone.0059685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607566/
https://www.ncbi.nlm.nih.gov/pubmed/23536886
http://dx.doi.org/10.1371/journal.pone.0059685

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