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Functional Impacts of NRXN1 Knockdown on Neurodevelopment in Stem Cell Models
Exonic deletions in NRXN1 have been associated with several neurodevelopmental disorders, including autism, schizophrenia and developmental delay. However, the molecular mechanism by which NRXN1 deletions impact neurodevelopment remains unclear. Here we used human induced pluripotent stem cells (hiP...
Autores principales: | Zeng, Liyun, Zhang, Peilin, Shi, Lingling, Yamamoto, Vicky, Lu, Wange, Wang, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607566/ https://www.ncbi.nlm.nih.gov/pubmed/23536886 http://dx.doi.org/10.1371/journal.pone.0059685 |
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