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Multivalent Human Papillomavirus L1 DNA Vaccination Utilizing Electroporation

OBJECTIVES: Naked DNA vaccines can be manufactured simply and are stable at ambient temperature, but require improved delivery technologies to boost immunogenicity. Here we explore in vivo electroporation for multivalent codon-optimized human papillomavirus (HPV) L1 and L2 DNA vaccination. METHODS:...

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Detalles Bibliográficos
Autores principales: Kwak, Kihyuck, Jiang, Rosie, Jagu, Subhashini, Wang, Joshua W., Wang, Chenguang, Christensen, Neil D., Roden, Richard B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607584/
https://www.ncbi.nlm.nih.gov/pubmed/23536912
http://dx.doi.org/10.1371/journal.pone.0060507