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Proteasome inhibitor (MG132) rescues Na(v)1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx(5cv) mice
The cardiac voltage-gated sodium channel, Na(v)1.5, plays a central role in cardiac excitability and impulse propagation and associates with the dystrophin multiprotein complex at the lateral membrane of cardiomyocytes. It was previously shown that Na(v)1.5 protein content and the sodium current (l(...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607792/ https://www.ncbi.nlm.nih.gov/pubmed/23532763 http://dx.doi.org/10.3389/fphys.2013.00051 |