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The Regulation of IGF-1 Gene Transcription and Splicing during Development and Aging
It is commonly known that the insulin-like growth factor-I gene contains six exons that can be differentially spliced to create multiple transcript variants. Further, there are two mutually exclusive leader exons each having multiple promoter sites that are variably used. The mature IGF-I protein de...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607797/ https://www.ncbi.nlm.nih.gov/pubmed/23533068 http://dx.doi.org/10.3389/fendo.2013.00039 |