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The Regulation of IGF-1 Gene Transcription and Splicing during Development and Aging

It is commonly known that the insulin-like growth factor-I gene contains six exons that can be differentially spliced to create multiple transcript variants. Further, there are two mutually exclusive leader exons each having multiple promoter sites that are variably used. The mature IGF-I protein de...

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Detalles Bibliográficos
Autor principal: Oberbauer, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607797/
https://www.ncbi.nlm.nih.gov/pubmed/23533068
http://dx.doi.org/10.3389/fendo.2013.00039

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