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A Quantitative Model of ERK MAP Kinase Phosphorylation in Crowded Media

Cytoplasm contains a large number of macromolecules at extremely high densities. How this striking nature of intracellular milieu called macromolecular crowding affects intracellular signaling remains uncharacterized. Here, we examined the effect of macromolecular crowding on ERK MAPK phosphorylatio...

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Detalles Bibliográficos
Autores principales: Aoki, Kazuhiro, Takahashi, Koichi, Kaizu, Kazunari, Matsuda, Michiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607838/
https://www.ncbi.nlm.nih.gov/pubmed/23528948
http://dx.doi.org/10.1038/srep01541

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