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12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma

The mechanisms underlying asthmatic airway epithelial injury are not clear. 12/15-lipoxygenase (an ortholog of human 15-LOX-1), which is induced by IL-13, is associated with mitochondrial degradation in reticulocytes at physiological conditions. In this study, we showed that 12/15-LOX expressed in n...

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Detalles Bibliográficos
Autores principales: Mabalirajan, Ulaganathan, Rehman, Rakhshinda, Ahmad, Tanveer, Kumar, Sarvesh, Leishangthem, Geeta Devi, Singh, Suchita, Dinda, Amit Kumar, Biswal, Shyam, Agrawal, Anurag, Ghosh, Balaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607899/
https://www.ncbi.nlm.nih.gov/pubmed/23528921
http://dx.doi.org/10.1038/srep01540