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Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B

BACKGROUND: Insulin and insulin-like growth factors (IGFs) act on tetrameric tyrosine kinase receptors controlling essential functions including growth, metabolism, reproduction and longevity. The insulin receptor (IR) binds insulin and IGFs with different affinities triggering different cell respon...

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Detalles Bibliográficos
Autores principales:	Giudice, Jimena, Barcos, Lucia Soledad, Guaimas, Francisco F, Penas-Steinhardt, Alberto, Giordano, Luciana, Jares-Erijman, Elizabeth A, Coluccio Leskow, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607927/ https://www.ncbi.nlm.nih.gov/pubmed/23497114 http://dx.doi.org/10.1186/1478-811X-11-18

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