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Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?

Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare. Benign conditions include Graves’ disease, toxic adenomas, congenital hyperthyroidism, and goiter. Differentiated thyroid cancer (DTC) and medulla...

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Autores principales: Breuer, Christopher, Tuggle, Charles, Solomon, Daniel, Sosa, Julie Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608013/
https://www.ncbi.nlm.nih.gov/pubmed/23149389
http://dx.doi.org/10.4274/Jcrpe.817
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author Breuer, Christopher
Tuggle, Charles
Solomon, Daniel
Sosa, Julie Ann
author_facet Breuer, Christopher
Tuggle, Charles
Solomon, Daniel
Sosa, Julie Ann
author_sort Breuer, Christopher
collection PubMed
description Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare. Benign conditions include Graves’ disease, toxic adenomas, congenital hyperthyroidism, and goiter. Differentiated thyroid cancer (DTC) and medullary thyroid carcinoma (MTC), with its related familial cancer syndromes, are the most common malignancies. Near-total or total thyroidectomy is the appropriate surgery for thyroid cancer, with/out central lymph node dissection. Emerging practice guidelines from professional societies are helpful, although they generally have not addressed surgical management of the pediatric patient. Thyroidectomy in children is associated with a higher rate of complications, such as recurrent laryngeal nerve injury and hypoparathyroidism, as compared to the surgery in adults. Therefore, it is essential that pediatric thyroidectomy be performed by high-volume thyroid surgeons, regardless of specialty. Case volume to support surgical expertise usually must be borrowed from the adult experience, given the relative paucity of pediatric thyroidectomies at an institutional level. These surgeons should work as part of a multidisciplinary team that includes pediatric endocrinologists and anesthesiologists, pediatricians, nuclear medicine physicians, and pathologists to afford children the best clinical outcomes. Conflict of interest:None declared.
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spelling pubmed-36080132013-03-27 Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children? Breuer, Christopher Tuggle, Charles Solomon, Daniel Sosa, Julie Ann J Clin Res Pediatr Endocrinol Review Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare. Benign conditions include Graves’ disease, toxic adenomas, congenital hyperthyroidism, and goiter. Differentiated thyroid cancer (DTC) and medullary thyroid carcinoma (MTC), with its related familial cancer syndromes, are the most common malignancies. Near-total or total thyroidectomy is the appropriate surgery for thyroid cancer, with/out central lymph node dissection. Emerging practice guidelines from professional societies are helpful, although they generally have not addressed surgical management of the pediatric patient. Thyroidectomy in children is associated with a higher rate of complications, such as recurrent laryngeal nerve injury and hypoparathyroidism, as compared to the surgery in adults. Therefore, it is essential that pediatric thyroidectomy be performed by high-volume thyroid surgeons, regardless of specialty. Case volume to support surgical expertise usually must be borrowed from the adult experience, given the relative paucity of pediatric thyroidectomies at an institutional level. These surgeons should work as part of a multidisciplinary team that includes pediatric endocrinologists and anesthesiologists, pediatricians, nuclear medicine physicians, and pathologists to afford children the best clinical outcomes. Conflict of interest:None declared. Galenos Publishing 2013-03 2013-03-01 /pmc/articles/PMC3608013/ /pubmed/23149389 http://dx.doi.org/10.4274/Jcrpe.817 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Breuer, Christopher
Tuggle, Charles
Solomon, Daniel
Sosa, Julie Ann
Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?
title Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?
title_full Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?
title_fullStr Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?
title_full_unstemmed Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?
title_short Pediatric Thyroid Disease: When is Surgery Necessary, and Who Should be Operating on Our Children?
title_sort pediatric thyroid disease: when is surgery necessary, and who should be operating on our children?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608013/
https://www.ncbi.nlm.nih.gov/pubmed/23149389
http://dx.doi.org/10.4274/Jcrpe.817
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