A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX

BACKGROUND: Genome-wide association studies (GWAS) identify regions of the genome that are associated with particular traits, but do not typically identify specific causative genetic elements. For example, while a large number of single nucleotide polymorphisms associated with type 2 diabetes (T2D)...

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Detalles Bibliográficos
Autores principales: Pendse, Jay, Ramachandran, Prasanna V, Na, Jianbo, Narisu, Narisu, Fink, Jill L, Cagan, Ross L, Collins, Francis S, Baranski, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608171/
https://www.ncbi.nlm.nih.gov/pubmed/23445342
http://dx.doi.org/10.1186/1471-2164-14-136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608171/
https://www.ncbi.nlm.nih.gov/pubmed/23445342
http://dx.doi.org/10.1186/1471-2164-14-136

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