Amino Acid Derivatives as New Zinc Binding Groups for the Design of Selective Matrix Metalloproteinase Inhibitors

A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging from rheumatoid arthritis to cardiomyopathy, periodontal disease, liver cirrhosis, multiple sclerosis, and cancer invasion and metastasis, where they showed to have a dual role, inhibiting or promotin...

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Detalles Bibliográficos
Autores principales: Giustiniano, Mariateresa, Tortorella, Paolo, Agamennone, Mariangela, Di Pizio, Antonella, Rossello, Armando, Nuti, Elisa, Gomez-Monterrey, Isabel, Novellino, Ettore, Campiglia, Pietro, Vernieri, Ermelinda, Sala, Marina, Bertamino, Alessia, Carotenuto, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608355/
https://www.ncbi.nlm.nih.gov/pubmed/23555050
http://dx.doi.org/10.1155/2013/178381

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