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The small molecule dispergo tubulates the endoplasmic reticulum and inhibits export
The mammalian endoplasmic reticulum (ER) is an organelle that maintains a complex, compartmentalized organization of interconnected cisternae and tubules while supporting a continuous flow of newly synthesized proteins and lipids to the Golgi apparatus. Using a phenotypic screen, we identify a small...
Autores principales: | Lu, Lei, Hannoush, Rami N., Goess, Brian C., Varadarajan, Shankar, Shair, Matthew D., Kirchhausen, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608490/ https://www.ncbi.nlm.nih.gov/pubmed/23389632 http://dx.doi.org/10.1091/mbc.E12-08-0575 |
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