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Response regulator–mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast

The Spc1 mitogen-activated protein kinase (MAPK) cascade in fission yeast is activated by two MAPK kinase kinase (MAPKKK) paralogues, Wis4 and Win1, in response to multiple forms of environmental stress. Previous studies identified Mcs4, a “response regulator” protein that associates with the MAPKKK...

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Detalles Bibliográficos
Autores principales: Morigasaki, Susumu, Ikner, Aminah, Tatebe, Hisashi, Shiozaki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608495/
https://www.ncbi.nlm.nih.gov/pubmed/23389634
http://dx.doi.org/10.1091/mbc.E12-10-0727