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Structural and Dynamical Insights on HLA-DR2 Complexes That Confer Susceptibility to Multiple Sclerosis in Sardinia: A Molecular Dynamics Simulation Study
Sardinia is a major Island in the Mediterranean with a high incidence of multiple sclerosis, a chronic autoimmune inflammatory disease of the central nervous system. Disease susceptibility in Sardinian population has been associated with five alleles of major histocompatibility complex (MHC) class I...
Autores principales: | Kumar, Amit, Cocco, Eleonora, Atzori, Luigi, Marrosu, Maria Giovanna, Pieroni, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608583/ https://www.ncbi.nlm.nih.gov/pubmed/23555757 http://dx.doi.org/10.1371/journal.pone.0059711 |
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