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Structural and Dynamical Insights on HLA-DR2 Complexes That Confer Susceptibility to Multiple Sclerosis in Sardinia: A Molecular Dynamics Simulation Study

Sardinia is a major Island in the Mediterranean with a high incidence of multiple sclerosis, a chronic autoimmune inflammatory disease of the central nervous system. Disease susceptibility in Sardinian population has been associated with five alleles of major histocompatibility complex (MHC) class I...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Cocco, Eleonora, Atzori, Luigi, Marrosu, Maria Giovanna, Pieroni, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608583/
https://www.ncbi.nlm.nih.gov/pubmed/23555757
http://dx.doi.org/10.1371/journal.pone.0059711

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