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Platelets Recognize Brain-Specific Glycolipid Structures, Respond to Neurovascular Damage and Promote Neuroinflammation

Platelets respond to vascular damage and contribute to inflammation, but their role in the neurodegenerative diseases is unknown. We found that the systemic administration of brain lipid rafts induced a massive platelet activation and degranulation resulting in a life-threatening anaphylactic-like r...

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Detalles Bibliográficos
Autores principales:	Sotnikov, Ilya, Veremeyko, Tatyana, Starossom, Sarah C., Barteneva, Natalia, Weiner, Howard L., Ponomarev, Eugene D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608633/ https://www.ncbi.nlm.nih.gov/pubmed/23555611 http://dx.doi.org/10.1371/journal.pone.0058979

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