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The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn’s disease

BACKGROUND: Crohn’s disease (CD) is associated with elevated anti-glycans antibody response in 60% of CD patients, and 25% of healthy first-degree relatives (HFDRs), suggesting a genetic influence for this humoral response. In mice, anti-glucan antibody response depends on the NLRP3 inflammasome. He...

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Detalles Bibliográficos
Autores principales:	Vasseur, Francis, Sendid, Boualem, Broly, Franck, Gower-Rousseau, Corinne, Sarazin, Aurore, Standaert-Vitse, Annie, Colombel, Jean-Frederic, Poulain, Daniel, Jouault, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608972/ https://www.ncbi.nlm.nih.gov/pubmed/23506543 http://dx.doi.org/10.1186/1471-2350-14-35

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