TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1

There is growing interest in identifying regulators of autophagy. The molecular mechanism underlying transforming growth factor-β activated kinase 1 (TAK1)-induced autophagy is poorly understood. We found that TAK1 inhibits p70 S6 kinase1 (S6K1) phosphorylation by interfering interaction of raptor w...

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Detalles Bibliográficos
Autores principales: Shin, Ju Hyun, Min, Sang-Hyun, Kim, Seong-Jin, Kim, Young-Il, Park, Junsoo, Lee, Heung Kyu, Yoo, Ook Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609023/
https://www.ncbi.nlm.nih.gov/pubmed/23532117
http://dx.doi.org/10.1038/srep01561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609023/
https://www.ncbi.nlm.nih.gov/pubmed/23532117
http://dx.doi.org/10.1038/srep01561

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