Cargando…

TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1

There is growing interest in identifying regulators of autophagy. The molecular mechanism underlying transforming growth factor-β activated kinase 1 (TAK1)-induced autophagy is poorly understood. We found that TAK1 inhibits p70 S6 kinase1 (S6K1) phosphorylation by interfering interaction of raptor w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Ju Hyun, Min, Sang-Hyun, Kim, Seong-Jin, Kim, Young-Il, Park, Junsoo, Lee, Heung Kyu, Yoo, Ook Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609023/ https://www.ncbi.nlm.nih.gov/pubmed/23532117 http://dx.doi.org/10.1038/srep01561

Ejemplares similares

Olea europaea Suppresses Inflammation by Targeting TAK1-Mediated MAP Kinase Activation
por: Song, Chaoran, et al.
Publicado: (2021)

The TGF(β)→TAK1→LATS→YAP1 Pathway Regulates the Spatiotemporal Dynamics of YAP1
por: Kim, Min-Kyu, et al.
Publicado: (2023)

Is TAK1 a Direct Upstream Kinase of AMPK?
por: Neumann, Dietbert
Publicado: (2018)

Methyloleanolate Induces Apoptotic And Autophagic Cell Death Via Reactive Oxygen Species Generation And c-Jun N-terminal Kinase Phosphorylation
por: Jeong, Myoung Seok, et al.
Publicado: (2019)

Torilin Inhibits Inflammation by Limiting TAK1-Mediated MAP Kinase and NF-κB Activation
por: Endale, Mehari, et al.
Publicado: (2017)

Switch‐associated protein 70 protects against nonalcoholic fatty liver disease through suppression of TAK1
por: Qian, Qiaofeng, et al.
Publicado: (2022)

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis
por: Geng, Jiefei, et al.
Publicado: (2017)

PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation
por: Han, Shuo, et al.
Publicado: (2021)

Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux
por: Kim, Hyunju, et al.
Publicado: (2016)

Dehydroabietic Acid Suppresses Inflammatory Response Via Suppression of Src-, Syk-, and TAK1-Mediated Pathways
por: Kim, Eunji, et al.
Publicado: (2019)

Identification and Functional Characterization of Novel Phosphorylation Sites in TAK1-Binding Protein (TAB) 1
por: Wolf, Alexander, et al.
Publicado: (2011)

HDAC1 Inactivation Induces Mitotic Defect and Caspase-Independent Autophagic Cell Death in Liver Cancer
por: Xie, Hong Jian, et al.
Publicado: (2012)

Monosodium Urate Crystal-Induced Chondrocyte Death via Autophagic Process
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease
por: Kim, Nami, et al.
Publicado: (2019)

TAK1ng control: TAK1 restrains NLRP3 activation
por: Mangan, Matthew Stephen, et al.
Publicado: (2018)

Distinct Roles of CK2- and AKT-Mediated NF-κB Phosphorylations in Clasmatodendrosis (Autophagic Astroglial Death) within the Hippocampus of Chronic Epilepsy Rats
por: Kim, Ji-Eun, et al.
Publicado: (2023)

TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity
por: van Caam, Arjan, et al.
Publicado: (2017)

Serine 389 phosphorylation of 3-phosphoinositide-dependent kinase 1 by UNC-51-like kinase 1 affects its ability to regulate Akt and p70 S6kinase
por: Kim, Kidae, et al.
Publicado: (2020)

Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
por: Kwon, Hyun Jung, et al.
Publicado: (2019)

Suppression of triple-negative breast cancer aggressiveness by LGALS3BP via inhibition of the TNF-α–TAK1–MMP9 axis
por: Sun, Eun-Gene, et al.
Publicado: (2023)

SWAP70 Overexpression Protects Against Pathological Cardiac Hypertrophy in a TAK1‐Dependent Manner
por: Qian, Qiaofeng, et al.
Publicado: (2023)

Cyclosporine A Induces Apoptotic and Autophagic Cell Death in Rat Pituitary GH3 Cells
por: Kim, Han Sung, et al.
Publicado: (2014)

Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress
por: Kim, Heejeong, et al.
Publicado: (2020)

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)
por: Keshwani, Malik M., et al.
Publicado: (2011)

Tripartite Motif‐Containing 27 Attenuates Liver Ischemia/Reperfusion Injury by Suppressing Transforming Growth Factor β–Activated Kinase 1 (TAK1) by TAK1 Binding Protein 2/3 Degradation
por: Chen, San‐Yang, et al.
Publicado: (2021)

ULK1 phosphorylates Exo70 to suppress breast cancer metastasis
por: Mao, Liyuan, et al.
Publicado: (2020)

Regulation of paclitaxel-induced programmed cell death by autophagic induction: A model for cervical cancer
por: Chi, Eun Young, et al.
Publicado: (2013)

Mediation of Autophagic Cell Death by Type 3 Ryanodine Receptor (RyR3) in Adult Hippocampal Neural Stem Cells
por: Chung, Kyung Min, et al.
Publicado: (2016)

Autophagic Organelles in DNA Damage Response
por: Kim, Jeongha, et al.
Publicado: (2021)

Anti-Inflammatory Activities of an Anti-Histamine Drug, Loratadine, by Suppressing TAK1 in AP-1 Pathway
por: Jang, Jiwon, et al.
Publicado: (2022)

Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells
por: Park, Jae Hyeon, et al.
Publicado: (2021)

Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses
por: Reiley, William W., et al.
Publicado: (2007)

Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation
por: Kao, C, et al.
Publicado: (2014)

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
por: Inbal, Boaz, et al.
Publicado: (2002)

Knockdown of CPEB1 and CPEB4 Inhibits Scar Formation via Modulation of TAK1 and SMAD Signaling
por: Cui, Hui Song, et al.
Publicado: (2023)

Autophagic Cell Death in Dictyostelium Requires the Receptor Histidine Kinase DhkM
por: Giusti, Corinne, et al.
Publicado: (2010)

Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation
por: Xu, Xiulong, et al.
Publicado: (2017)

Pyrrole-Derivative of Chalcone, (E)-3-Phenyl-1-(2-Pyrrolyl)-2-Propenone, Inhibits Inflammatory Responses via Inhibition of Src, Syk, and TAK1 Kinase Activities
por: Yang, Sungjae, et al.
Publicado: (2016)

Autophagic Cell Death and Cancer
por: Shimizu, Shigeomi, et al.
Publicado: (2014)

Regulation of autophagic cell death by glycogen synthase kinase-3β in adult hippocampal neural stem cells following insulin withdrawal
por: Ha, Shinwon, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mlrbhoml005t5qqd163qsljdmk