Cargando…

Stimulation of Autophagy Improves Endoplasmic Reticulum Stress–Induced Diabetes

Accumulation of misfolded proinsulin in the β-cell leads to dysfunction induced by endoplasmic reticulum (ER) stress, with diabetes as a consequence. Autophagy helps cellular adaptation to stress via clearance of misfolded proteins and damaged organelles. We studied the effects of proinsulin misfold...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bachar-Wikstrom, Etty, Wikstrom, Jakob D., Ariav, Yafa, Tirosh, Boaz, Kaiser, Nurit, Cerasi, Erol, Leibowitz, Gil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609555/ https://www.ncbi.nlm.nih.gov/pubmed/23274896 http://dx.doi.org/10.2337/db12-1474

Ejemplares similares

Glucose Amplifies Fatty Acid-Induced Endoplasmic Reticulum Stress in Pancreatic β-Cells via Activation of mTORC1
por: Bachar, Etti, et al.
Publicado: (2009)

Endoplasmic reticulum stress in human chronic wound healing: Rescue by 4‐phenylbutyrate
por: Bachar‐Wikstrom, Etty, et al.
Publicado: (2020)

β‐Cell failure in type 2 diabetes
por: Leibowitz, Gil, et al.
Publicado: (2011)

Darier Disease – A Multi-organ Condition?
por: BACHAR-WIKSTRÖM, Etty, et al.
Publicado: (2021)

Multifaceted roles of mitochondria in wound healing and chronic wound pathogenesis
por: Hunt, Matthew, et al.
Publicado: (2023)

Correction: AMP-Activated Protein Kinase (AMPK) Mediates Nutrient Regulation of Thioredoxin-Interacting Protein (TXNIP) in Pancreatic Beta-Cells
por: Shaked, Maayan, et al.
Publicado: (2012)

AMP-Activated Protein Kinase (AMPK) Mediates Nutrient Regulation of Thioredoxin-Interacting Protein (TXNIP) in Pancreatic Beta-Cells
por: Shaked, Maayan, et al.
Publicado: (2011)

Patients with Darier Disease Exhibit Cognitive Impairment while Patients with Hailey-Hailey Disease Do Not: An Experimental, Matched Case-control Study
por: CURMAN, Philip, et al.
Publicado: (2021)

Hailey-Hailey Disease is Associated with Diabetes: A Population-based Cohort Study, Clinical Cohort Study, and Pedigree Analysis
por: CURMAN, Philip, et al.
Publicado: (2023)

Metabolic phenotype in Darier disease: a cross-sectional clinical study
por: Ahanian, Tara, et al.
Publicado: (2020)

Darier disease is associated with heart failure: a cross-sectional case-control and population based study
por: Bachar-Wikstrom, Etty, et al.
Publicado: (2020)

Identification of Novel Glycans in the Mucus Layer of Shark and Skate Skin
por: Bachar-Wikstrom, Etty, et al.
Publicado: (2023)

Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors
por: Kogot-Levin, Aviram, et al.
Publicado: (2020)

Apoptosis, autophagy & endoplasmic reticulum stress in diabetes mellitus
por: Demirtas, Levent, et al.
Publicado: (2016)

HCV Causes Chronic Endoplasmic Reticulum Stress Leading to Adaptation and Interference with the Unfolded Protein Response
por: Merquiol, Emmanuelle, et al.
Publicado: (2011)

Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells
por: Quan, Wenying, et al.
Publicado: (2012)

Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects
por: Martínez-Pizarro, Ainhoa, et al.
Publicado: (2016)

Role of Endoplasmic Reticulum Stress, Autophagy, and Inflammation in Cardiovascular Disease
por: Zhang, Cheng, et al.
Publicado: (2017)

Mitochondrial-Endoplasmic Reticulum Communication-Mediated Oxidative Stress and Autophagy
por: Liu, Xiaoqing, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress and Autophagy Are Involved in Hepatotoxicity Induced by Tributyltin
por: Liang, Weiqi, et al.
Publicado: (2023)

Induction of endoplasmic reticulum stress and unfolded protein response constitutes a pathogenic strategy of group A streptococcus
por: Baruch, Moshe, et al.
Publicado: (2014)

Effects of homocysteine-induced endoplasmic reticulum protein on endoplasmic reticulum stress, autophagy, and neuronal apoptosis following intracerebral hemorrhage
por: Wu, Hui, et al.
Publicado: (2020)

Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response()
por: Haberzettl, Petra, et al.
Publicado: (2013)

Kazinol C from Broussonetia kazinoki stimulates autophagy via endoplasmic reticulum stress-mediated signaling
por: Lee, Yunkyeong, et al.
Publicado: (2022)

Autophagy, Endoplasmic Reticulum Stress and the Unfolded Protein Response in Intracerebral Hemorrhage
por: Niu, Mingming, et al.
Publicado: (2017)

Role of Autophagy in Cancer Cell Response to Nucleolar and Endoplasmic Reticulum Stress
por: Pecoraro, Annalisa, et al.
Publicado: (2020)

The Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson’s Disease
por: Ren, Haigang, et al.
Publicado: (2021)

Autophagy and Endoplasmic Reticulum Stress during Onset and Progression of Arrhythmogenic Cardiomyopathy
por: Pitsch, Mark, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells
por: Moon, Seoil, et al.
Publicado: (2022)

Crosstalk between endoplasmic reticulum stress response and autophagy in human diseases
por: Kwon, Junhee, et al.
Publicado: (2023)

Endoplasmic reticulum stress and diabetic retinopathy
por: Oshitari, Toshiyuki, et al.
Publicado: (2008)

Endoplasmic Reticulum Stress and Diabetic Cardiomyopathy
por: Xu, Jiancheng, et al.
Publicado: (2012)

Monascuspiloin Enhances the Radiation Sensitivity of Human Prostate Cancer Cells by Stimulating Endoplasmic Reticulum Stress and Inducing Autophagy
por: Chiu, Hui-Wen, et al.
Publicado: (2012)

Atlastins remodel the endoplasmic reticulum for selective autophagy
por: Liang, Jin Rui, et al.
Publicado: (2018)

ER‐phagy: selective autophagy of the endoplasmic reticulum
por: Mochida, Keisuke, et al.
Publicado: (2022)

Trafficking-defective mutant PROKR2 cycles between endoplasmic reticulum and Golgi to attenuate endoplasmic reticulum stress
por: Song, Yong Bhum, et al.
Publicado: (2022)

Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy
por: Hong, Seong-Ho, et al.
Publicado: (2016)

Autophagy decreases alveolar macrophage apoptosis by attenuating endoplasmic reticulum stress and oxidative stress
por: Fan, Tao, et al.
Publicado: (2016)

Endoplasmic Reticulum Homeostasis Regulates TLR4 Expression and Signaling in Mast Cells
por: Boukeileh, Shatha, et al.
Publicado: (2022)

Abortive Autophagy Induces Endoplasmic Reticulum Stress and Cell Death in Cancer Cells
por: Claerhout, Sofie, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qc9rhkpkvlccafi7g9a0h3qa8n