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TGFβ Receptor Signaling Is Essential for Inflammation-Induced but Not β-Cell Workload–Induced β-Cell Proliferation
Protection and restoration of a functional β-cell mass are fundamental strategies for prevention and treatment of diabetes. Consequently, knowledge of signals that determine the functional β-cell mass is of immense clinical relevance. Transforming growth factor β (TGFβ) superfamily signaling pathway...
Autores principales: | Xiao, Xiangwei, Wiersch, John, El-Gohary, Yousef, Guo, Ping, Prasadan, Krishna, Paredes, Jose, Welsh, Carey, Shiota, Chiyo, Gittes, George K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609557/ https://www.ncbi.nlm.nih.gov/pubmed/23248173 http://dx.doi.org/10.2337/db12-1428 |
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