Cargando…

Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle

In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is activated by muscle contraction and regulates contrac...

Descripción completa

Detalles Bibliográficos
Autores principales: Sylow, Lykke, Jensen, Thomas E., Kleinert, Maximilian, Mouatt, Joshua R., Maarbjerg, Stine J., Jeppesen, Jacob, Prats, Clara, Chiu, Tim T., Boguslavsky, Shlomit, Klip, Amira, Schjerling, Peter, Richter, Erik A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609592/
https://www.ncbi.nlm.nih.gov/pubmed/23274900
http://dx.doi.org/10.2337/db12-0491