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Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle
In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is activated by muscle contraction and regulates contrac...
Autores principales: | Sylow, Lykke, Jensen, Thomas E., Kleinert, Maximilian, Mouatt, Joshua R., Maarbjerg, Stine J., Jeppesen, Jacob, Prats, Clara, Chiu, Tim T., Boguslavsky, Shlomit, Klip, Amira, Schjerling, Peter, Richter, Erik A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609592/ https://www.ncbi.nlm.nih.gov/pubmed/23274900 http://dx.doi.org/10.2337/db12-0491 |
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