The Alkaloid Compound Harmane Increases the Lifespan of Caenorhabditis elegans during Bacterial Infection, by Modulating the Nematode’s Innate Immune Response

The nematode Caenorhabditis elegans has in recent years been proven to be a powerful in vivo model for testing antimicrobial compounds. We report here that the alkaloid compound Harmane (2-methyl-β-carboline) increases the lifespan of nematodes infected with a human pathogen, the Shiga toxin-produci...

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Detalles Bibliográficos
Autores principales: Jakobsen, Henrik, Bojer, Martin S., Marinus, Martin G., Xu, Tao, Struve, Carsten, Krogfelt, Karen A., Løbner-Olesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609739/
https://www.ncbi.nlm.nih.gov/pubmed/23544153
http://dx.doi.org/10.1371/journal.pone.0060519

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