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Quantitative Phenotyping of Duchenne Muscular Dystrophy Dogs by Comprehensive Gait Analysis and Overnight Activity Monitoring
The dystrophin-deficient dog is excellent large animal model for testing novel therapeutic modalities for Duchenne muscular dystrophy (DMD). Despite well-documented descriptions of dystrophic symptoms in these dogs, very few quantitative studies have been performed. Here, we developed a comprehensiv...
Autores principales: | Shin, Jin-Hong, Greer, Brian, Hakim, Chady H., Zhou, Zhongna, Chung, Yu-chia, Duan, Ye, He, Zhihai, Duan, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609742/ https://www.ncbi.nlm.nih.gov/pubmed/23544107 http://dx.doi.org/10.1371/journal.pone.0059875 |
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