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Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1

Protein-based therapeutics feature large interacting surfaces. Protein folding endows structural stability to localised surface epitopes, imparting high affinity and target specificity upon interactions with binding partners. However, short synthetic peptides with sequences corresponding to such pro...

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Detalles Bibliográficos
Autores principales:	Rao, Tara, Ruiz-Gómez, Gloria, Hill, Timothy A., Hoang, Huy N., Fairlie, David P., Mason, Jody M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609778/ https://www.ncbi.nlm.nih.gov/pubmed/23544065 http://dx.doi.org/10.1371/journal.pone.0059415

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