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SeqEntropy: Genome-Wide Assessment of Repeats for Short Read Sequencing

BACKGROUND: Recent studies on genome assembly from short-read sequencing data reported the limitation of this technology to reconstruct the entire genome even at very high depth coverage. We investigated the limitation from the perspective of information theory to evaluate the effect of repeats on s...

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Detalles Bibliográficos
Autores principales: Chu, Hsueh-Ting, Hsiao, William WL., Tsao, Theresa TH., Hsu, D. Frank, Chen, Chaur-Chin, Lee, Sheng-An, Kao, Cheng-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609794/
https://www.ncbi.nlm.nih.gov/pubmed/23544073
http://dx.doi.org/10.1371/journal.pone.0059484

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