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Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen
Foot-and-mouth disease remains a major plague of livestock and outbreaks are often economically catastrophic. Current inactivated virus vaccines require expensive high containment facilities for their production and maintenance of a cold-chain for their activity. We have addressed both of these majo...
Autores principales: | Porta, Claudine, Kotecha, Abhay, Burman, Alison, Jackson, Terry, Ren, Jingshan, Loureiro, Silvia, Jones, Ian M., Fry, Elizabeth E., Stuart, David I., Charleston, Bryan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609824/ https://www.ncbi.nlm.nih.gov/pubmed/23544011 http://dx.doi.org/10.1371/journal.ppat.1003255 |
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