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Allostery and instability in the functional plasticity of synaptotagmin I

Synaptotagmin I (Syt I) is the calcium ion sensor for regulated release of neurotransmitter. How Syt I mediates this cellular event has been a question of extensive study for decades and yet, a clear understanding of the protein’s diverse functionality has remained elusive. Using tools of thermodyna...

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Detalles Bibliográficos
Autores principales: Fealey, Michael E., Hinderliter, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609835/
https://www.ncbi.nlm.nih.gov/pubmed/23750295
http://dx.doi.org/10.4161/cib.22830