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CRF acts in the midbrain to attenuate accumbens dopamine release to rewards but not their predictors

Stressors impact dopamine-dependent behaviors such as motivation, though the underlying neurobiological mechanism is not well defined. We report that corticotropin-releasing factor (CRF) acts within the ventral tegmental area (VTA) to reduce the motivation to work for food rewards. CRF in the VTA re...

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Detalles Bibliográficos
Autores principales: Wanat, Matthew J., Bonci, Antonello, Phillips, Paul E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609940/
https://www.ncbi.nlm.nih.gov/pubmed/23416448
http://dx.doi.org/10.1038/nn.3335