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Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial
BACKGROUND: Lithium has neuroprotective effects in cell and animal models of amyotrophic lateral sclerosis (ALS), and a small pilot study in patients with ALS showed a significant effect of lithium on survival. We aimed to assess whether lithium improves survival in patients with ALS. METHODS: The l...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Lancet Pub. Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610091/ https://www.ncbi.nlm.nih.gov/pubmed/23453347 http://dx.doi.org/10.1016/S1474-4422(13)70037-1 |