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A general approach to break the concentration barrier in single-molecule imaging
Single-molecule fluorescence imaging is often incompatible with physiological protein concentrations, as fluorescence background overwhelms an individual molecule's signal. We solve this problem with a new imaging approach called PhADE (PhotoActivation, Diffusion, and Excitation). A protein of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610324/ https://www.ncbi.nlm.nih.gov/pubmed/22961247 http://dx.doi.org/10.1038/nmeth.2174 |