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Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells
Tumor necrosis factor-alpha (TNF-α) was reported as anticancer therapy due to its cytotoxic effect against an array of tumor cells. However, its undesirable responses of TNF-α on activating NF-κB signaling and pro-metastatic property limit its clinical application in treating cancers. Therefore, sen...
Autores principales: | Wong, Vincent Kam Wai, Zhang, Molly Miao, Zhou, Hua, Lam, Kelly Yin Ching, Chan, Po Ling, Law, Carmen Ka Man, Yue, Patrick Ying Kit, Liu, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610377/ https://www.ncbi.nlm.nih.gov/pubmed/23573150 http://dx.doi.org/10.1155/2013/745295 |
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