A Randomized, Double-Blind Placebo Controlled Trial of Balapiravir, a Polymerase Inhibitor, in Adult Dengue Patients

Background. Dengue is the most common arboviral infection of humans. There are currently no specific treatments for dengue. Balapiravir is a prodrug of a nucleoside analogue (called R1479) and an inhibitor of hepatitis C virus replication in vivo. Methods. We conducted in vitro experiments to determ...

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Detalles Bibliográficos
Autores principales: Nguyen, Nguyet Minh, Tran, Chau Nguyen Bich, Phung, Lam Khanh, Duong, Kien Thi Hue, Huynh, Huy le Anh, Farrar, Jeremy, Nguyen, Quyen Than Ha, Tran, Hien Tinh, Nguyen, Chau Van Vinh, Merson, Laura, Hoang, Long Truong, Hibberd, Martin L., Aw, Pauline P. K., Wilm, Andreas, Nagarajan, Niranjan, Nguyen, Dung Thi, Pham, Mai Phuong, Nguyen, Truong Thanh, Javanbakht, Hassan, Klumpp, Klaus, Hammond, Janet, Petric, Rosemary, Wolbers, Marcel, Nguyen, Chinh Tran, Simmons, Cameron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610419/
https://www.ncbi.nlm.nih.gov/pubmed/22807519
http://dx.doi.org/10.1093/infdis/jis470

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